The Sox fell to a season-worse 31 games under .500 in the loss.
The Indians added two runs in the fifth inning while chasing left-handed starter Hector Santiago (4-9, 3.53 ERA). Nick Swisher led off with a walk before Jason Kipnis singled. Right-hander Jacob Petricka replaced Santiago and gave up a one-out RBI single to Ryan Raburn before hitting Cabrera to load the bases. Michael Brantley hit a sacrifice fly to left field to push the Indians’ lead to 3-0.
Santiago (4-9, 3.53 ERA) allowed six hits and three runs, struck out and walked three in four innings.
Indians’ starter Danny Salazar (1-2, 2.66 ERA) gave up four hits, struck out nine and walked two in just 3 2/3 innings.
The Sox fell to 30 games below .500 for the first time since 1976 on Thursday night and have 15 games remaining, 14 against the AL Central and one game against the Toronto Blue Jays.